Patriots and 49ers top the lopsided end of the NFL Week 6 board at 76% and 78%

New England at 76% and San Francisco at 78% sit among the heavy favorites in the NFL Week 6 snapshot supplied with this report. But they are not alone at the board’s more uneven end: according to defirate.com, the Los Angeles Rams are the week’s biggest favorite, while Kansas City also holds a substantial market advantage.

The outlet’s comparison covers Kalshi and Polymarket US winner markets for all 14 matchups, with prices captured at 11:46 a.m. ET on October 13. The percentages represent purchase prices before fees—not final results or prices guaranteed to remain available before kickoff.

Favorites face divisional opponents

New England hosts the New York Jets at Gillette Stadium on Sunday, October 18, at 1 p.m. ET. Both teams arrive after victories: the Patriots reached 3-2 by beating Las Vegas 45-17, while the Jets improved to 2-3 with a 17-12 win over Cleveland, according to defirate.com.

San Francisco closes the schedule against Washington at Levi’s Stadium on Monday, October 19, at 8:15 p.m. ET. The 49ers are 5-0 after defeating Seattle 32-29; the Commanders are 1-3-1 after a 27-27 overtime tie with the Giants. Washington’s quoted price is 23%, against San Francisco’s 78%.

Closer games show snapshot-to-snapshot changes

Thursday’s opener on October 15 has Seattle at 59% and Denver at 42%, with both teams entering at 3-2. Seattle’s Kalshi price increased from 57% in defirate.com’s October 10 snapshot. Jacksonville, meanwhile, declined from 62% to 57% ahead of its London meeting with Houston, priced at 44%, on Sunday, October 18.

Green Bay’s Kalshi price rose from 48% to 53%, reversing Dallas’s advantage in the October 10 snapshot. Dallas is now quoted at 49% for the Sunday night game at Lambeau Field. Defirate.com also identifies Panthers–Eagles as a relatively balanced matchup; the changes it reports compare two article snapshots rather than opening prices.

What it means for prediction markets

• Heavy favorites are a group, not a two-team ranking. The Patriots and 49ers have pronounced advantages, but defirate.com identifies the Rams as the largest favorite.
• Price comparisons need a timestamp. The Week 6 quotes were captured on October 13, leaving time for changes before games begin.
• Purchase prices are not a normalized probability pair. San Francisco and Washington’s displayed prices total 101%, while Green Bay and Dallas total 102%, before fees.
• The clearest documented shift is Green Bay’s reversal. Its move from 48% to 53% changed the favored side between the October 10 and October 13 snapshots; it does not establish movement from the market open.